A Memorandum of Understanding (MoU) establishes a close, long-term cooperation between institutions.
| GANIL Partners | Aim | Start | End |
| FAZIA | FAZIA experimental phase | October 2018 | September 2023 |
| AGATA | Operation of AGATA detector | January 2016 | December 2020 |
| CNA (Spain) | Developments for S3 | December 2014 | December 2017 |
| NCSRD (Greece) | Developments for SPIRAL & SPIRAL2 | November 2013 | November 2016 |
| INFN/LNS (Italy) | LEBT & MEBT Choppers | July 2013 | June 2016 |
| IBS (South Korea) | Scientific and technological cooperation in particular for the Rare Isotope Science Project (RISP) and SPIRAL2 | May 2013 | April 2018 |
| SCK-CEN (Belgium) | Construction-related activities for SPIRAL, SPIRAL2 and for upgrades of the RIB capabilities | October 2012 | September 2015 |
| TRIUMF (Canada) | Improvement and Development of Facilities to produce ion-beams of short-lived rare isotopes | August 2012 | December 2014 |
| NEDA | Construction and operation of the NEDA project | March 2012 | December 2020 |
| PARIS | Construction of the PARIS Demonstrator | January 2012 | December 2015 |
| NFS | Construction and commissioning of the NFS facility | January 2012 | December 2015 |
| EURISOL | Development of EURISOL | November 2011 | |
| FAZIA | Construction of the FAZIA demonstrator | October 2011 | December 2015 |
| ESS Bilbao (Spain) | Collaboration in scientific research and development of joint actions in the field of High Power Linear Accelerator and their Applications | March 2011 | March 2016 |
| Uppsala University (Sweden) | General framework of collaboration and project relationships | December 2009 | December 2014 |
| IMP (China) | General framework of collaboration and project relationships | April 2009 | April 2012 |
| BARC-TIRF (India) | General framework of collaboration and project relationships | June 2008 | June 2013 |
| INFN (Italy) | Construction of radioactive beams facilities Spes at LNL and SPIRAL2 at GANIL | April 2009 | April 2014 |
| MSU (USA) | General framework of collaboration and project relationships | May 2008 | May 2011 |
| INRNE (Bulgaria) | General framework of collaboration and project relationships | April 2008 | April 2011 |
| ANL (USA) | Nuclear Physics, Research and Development Cooperation | April 2007 | Mars 2012 |
| HRIBF/ORNL (USA) | General framework of collaboration and project relationships | April 2007 | April 2011 |
| SOREQ (Israel) | Cooperation to advance heavy ion physics with beams of stable and rare isotopes | May 2006 | May 2011 |
| FLNR/JINR (Russia) | Heavy ion physics with beams of short-lived rare isotopes | April 2006 | |
| NIPNE (Romania) | General framework of collaboration and project relationships | March 2006 | |
| CERN/ISOLDE (Switzerland) | General framework of collaboration and project relationships | February 2004 | |
| GSI (Germany) | General framework of collaboration and project relationships | March 2002 | March 2008 |
